Morphological changes in the testes of white rats and humans in acute and chronic alcoholic intoxications: Experimental and sectional study

BACKGROUND: This study analyzed the effects of ethyl alcohol and narcotic drugs on male reproductive organs. Practically no studies have examined morphological transformations in testicles during intoxication, which, at current level ethanol consumption by men age, is a social medical problem that far from being solved.
 AIM: Through short-term long-term experiments, this aimed to examine severity dynamics changes gonads intoxication mature rats comparison with those individuals who died alcoholic disease severe catamnesis.
 MATERIAL AND METHODS: The sexually were subjected acute chronic intoxications (from 2 weeks 6 months) persons which was found blood (at least 5 promile) catamnesis noted.
 RESULTS: In both experimental sectional materials, stroma characterized circulatory disorders plethora stasis post-capillaries small veins, edema, perivascular interstitial sclerosis. inhibition spermatogenesis material more pronounced, indicated main etiopathological factor these changes.
 CONCLUSION: Chronic has damaging directly, testicular parenchyma, indirectly overlying links system (hypothalamus pituitary gland). neurotoxic, microangiopathic, disenergetic inhibit normal spermatogenesis. Ultimately, negative effect based analysis observed hypotesticular conditions manifestations wasting syndrome.